Drug Repurposing (Project Rephetio)

Used hetnet edge prediction to predict whether each of 1,538 compounds treats each of 136 diseases. Browse this study's 209,168 predictions and the evidence behind them to explore new uses for existing drugs.

From Himmelstein et al (2017) eLife

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Prioritizing Disease-Associated Genes

Used hetnet edge prediction for disease-associated genes, based on a predecessor network to Hetionet. Browse this study's 55,4364 results to prioritize genome-wide association studies by narrowing down the search.

From Himmelstein et al (2015) PLOS Computational Biology

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XSwap Edge Probability Baselines

Explores the probability of edge existence due to node degree and provides a baseline for network-based predictions.

From Zietz et al (2024) GigaScience